Top 10 Accidental Discoveries
- Published February 24, 2008 - 90 Comments
Some of man’s greatest discoveries have been made entirely by accident. If it weren’t for many of these things, life would be very different for us. This is a list of the 10 greatest accidental discoveries.
10. Viagra

Millions of men around the world owe a salute to the hard working stiffs in the Welsh village of Merthyr Tydfil where, in 1992, their hard work testing this new angina drug produced firm evidence of its unexpected sex enhancing power. This discovery would be much higher on the list if it weren’t for the fact that it is the cause of 90% of the spam I receive every day!
9. Chocolate Chip Cookies

According to Nestle, Mrs. Wakefield (owner of the Toll House Inn) was making chocolate cookies but ran out of regular baker’s chocolate, so she substituted it with broken pieces of semi-sweet chocolate, thinking that it would melt and mix into the batter. It clearly did not, and the chocolate chip cookie was born. Wakefield sold the recipe to Nestle in exchange for a lifetime supply of chocolate chips (instead of patenting it and making billions!) Every bag of Nestle chocolate chips in North America has a variation of her original recipe printed on the back (margarine is now included both as a variant on butter and for those people who want to pretend it is healthy).
8. Popsicles

The Popsicle was invented by an 11 year who kept it secret for 18 years. The inventor was Frank Epperson who, in 1905, left a mixture of powdered soda and water out on the porch, which contained a stir stick. That night, temperatures in San Francisco reached a record low. When he woke the next morning, he discovered that it had frozen to the stir stick, creating a fruit flavored ice treat that he humbly named the epsicle. 18 years later he patented it and called it the Popsicle.
7. Artificial Sweetener

Like many artificial sweeteners, the sweetness of cyclamate was discovered by accident. Michael Sveda was working in the lab on the synthesis of anti-fever medication. He put his cigarette down on the lab bench and when he put it back in his mouth he discovered the sweet taste of cyclamate. Cancer inducing Aspartame was discovered in 1965 by James M. Schlatter, a chemist working for G.D. Searle & Company. Schlatter had synthesized aspartame in the course of producing an anti-ulcer drug candidate. He discovered its sweet taste serendipitously when he licked his finger, which had accidentally become contaminated with aspartame. Saccharin (the oldest artificial sweetener) was first produced in 1878 by Constantin Fahlberg, a chemist working on coal tar derivatives in Ira Remsen’s laboratory at the Johns Hopkins University, and it was he who, accidentally, discovered its intensely sweet nature.
6. Brandy

Initially wine was distilled as a preservation method and as a way to make the wine easier for merchants to transport. It was also thought that wine was originally distilled to lessen the tax which was assessed by volume. The intent was to add the water removed by distillation back to the brandy shortly before consumption. It was discovered that after having been stored in wooden casks, the resulting product had improved over the original distilled spirit. No one is sure who it was that discovered the delightful taste of this distilled liquor, but he was clearly guided by God in its discovery for the betterment of man.
5. Teflon

Teflon was invented accidentally by Roy Plunkett of Kinetic Chemicals in 1938. Plunkett was attempting to make a new CFC refrigerant, the perfluorethylene polymerized (say that 3 times fast!) in a pressurized storage container. In this original chemical reaction, iron from the inside of the container acted as a catalyst. In 1954, French engineer Marc Grégoire created the first pan coated with Teflon non-stick resin under the brand name of Tefal after his wife urged him to try the material, that he’d been using on fishing tackle, on her cooking pans. Teflon is inert to virtually all chemicals and is considered the most slippery material in existence – second only to the political wrangling of President George Bush.
4. Microwave

Percy LeBaron Spencer of the Raytheon Company was walking past a radar tube and he noticed that the chocolate bar in his pocket melted. Realizing that he might be on to a hot new product he placed a small bowl of popcorn in front of the tube and it quickly popped all over the room. Tens of millions of lazy cooks now have him to thank for their dull food!
3. Potato Chips

The first potato chip was invented by George Crum (half American Indian half African American) at Moon’s Lake House near Saratoga Springs, New York, on August 24, 1853. He was fed up with the constant complaints of a customer who kept sending his potatoes back to the kitchen because they were too thick and soggy. Crum decided to slice the potatoes so thin that they couldn’t be eaten with a fork. Against Crum’s expectation, the customer was ecstatic about the new chips. They became a regular item on the lodge’s menu under the name “Saratoga Chips” and a large contributing factor of the Western world’s obesity problems.
2. LSD

LSD was first synthesized on November 16, 1938 by Swiss chemist Dr. Albert Hofmann at the Sandoz Laboratories in Basel, Switzerland, as part of a large research program searching for medically useful ergot alkaloid derivatives. Its psychedelic properties were unknown until 5 years later, when Hofmann, acting on what he has called a “peculiar presentiment,” returned to work on the chemical. While re-synthesizing LSD-25 for further study on April 16, 1943, Hofmann became dizzy and was forced to stop work. In his journal, Hofmann wrote that after becoming dizzy he proceeded home and was affected by a “remarkable restlessness, combined with a slight dizziness”. Hofmann stated that as he lay in his bed he sank into a not unpleasant “intoxicated like condition” which was characterized by an extremely stimulated imagination. He stated that he was in a dreamlike state, and with his eyes closed he could see uninterrupted streams of “fantastic pictures, extraordinary shapes with intense, kaleidoscopic play of colors.” The condition lasted about two hours after which it faded away. Following this, he took a massive dose on what has become known as Bicycle Day. You can read more about Bicycle day on Wikipedia. It is worth the read!
1. Penicillin

In 1928, Scottish Scientist Sir Alexander Fleming was studying Staphylococcus – the bacteria that causes food poisoning. He turned up at work one day and discovered a blue-green mould that seemed to be inhibiting growth of the bacteria. He grew a pure culture of the mould and discovered that it was a Penicillium mould. After further experiments, Fleming was convinced that penicillin could not last long enough in the human body to kill pathogenic bacteria, and stopped studying it after 1931, but restarted some clinical trials in 1934 and continued to try to get someone to purify it until 1940. The development of penicillin for use as a medicine is attributed to the Australian Nobel Laureate Howard Walter Florey – he shared the Nobel Prize with Fleming and Ernst Boris Chain.
This list quotes verbatim from the Wikipedia article Lysergic Acid Diethylamide.
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February 24th, 2008 at 12:29 pm
I can’t believe I just did that. I need help.
February 24th, 2008 at 12:29 pm
my number 1 accidental discovery Listverse!
February 24th, 2008 at 1:06 pm
jfrater: it spams my inbox too.
I knew atleast6 of these were accidental, but my all-time favorite snack chocolate chip cookies were accidental? If there is a god, he must have thought of every fat kid in America when he made that accident!
February 24th, 2008 at 1:09 pm
Jamie, nice pic on viagra! LOL!
February 24th, 2008 at 1:11 pm
I thought Reagan was the Teflon President
February 24th, 2008 at 1:12 pm
I always thought potato chips were invented by some irish guy, weird! (BTW does that make me racist? LOL!)
February 24th, 2008 at 1:14 pm
Have you noticed they all fit into the following categories: Sex, drugs, food, alcohol. Excellent accidents!
February 24th, 2008 at 1:14 pm
David: Nope, its Bush Jr. and the reason why he is the teflon president is because he is a decendant of Franklin Pierce, a president who was pro-slavery and pretty much pro anything that was bad.
February 24th, 2008 at 1:15 pm
another kiwi: hmmm,,, that is weird!
February 24th, 2008 at 1:16 pm
is it weird that the pic on #8 gave me what viagra gives you?
February 24th, 2008 at 1:20 pm
The best part of the penicillin discovery? The REASON the spores were on his slides was because he was a terrible house keeper and had moldy sandwiches, food, etc. lying around his house. Due to the less than sterile conditions of his laboratory, his slides were cross-contaminated, leading to his discovery of penicillin… I used that argument so many times with my mom as a reason not to clean my room… funnily enough, it never worked
February 24th, 2008 at 1:56 pm
Who ever thought you could make something extraordinary on accident.
February 24th, 2008 at 2:29 pm
“Cancer inducing Aspartame”
I think that is a bit strong, unless you are referring only to studies involving rodents. There is no compelling evidence supporting this with respect to humans. Not to mention, it is one of the most common sweeteners used globally in diet soft-drinks (the ingredients of which are – understandably – subject to rigorous government approvals processes).
February 24th, 2008 at 2:39 pm
how can the discovery of fire possibly not be on this list?
February 24th, 2008 at 3:01 pm
Post-its were another accidental discovery I beleive. They tried to make a strong glue but ended up making a weaker one, which the figured would be useful for making little sticky notes. Or something like that…
February 24th, 2008 at 3:02 pm
#7 ‘put his cigarette down on the lab bench’ – And I used to get told off for smoking in the lab. It’s Health and Safety gone mad.
I’m sure I read somewhere that vulcanisation of rubber was an accidental discovery. Where would that fit into AnotherKiwi’s list? Other than a special sub-category of sex.
February 24th, 2008 at 3:18 pm
Butterfish: You work in a lab?? Me too! Damn OSHA!
February 24th, 2008 at 3:21 pm
Cool list. I was thinking of submitting one like this myself. Some that I found that you do not have:
Coca-Cola- originally conceived as a patent medicine designed to cure many diseases including, but not limited to, headaches and impotence.
Super glue – discovered by Harry Coover who was trying to design a plastic gun-sight lens but found that the substance kept sticking to everything instead.
Safety glass- can’t remember the story behind this one, but essentially some scientist dropped a beaker and saw that the liquid inside had tempered the glass so it would break but not shatter.
Americas- a bit controversial since Columbus wasn’t the first to “discover” the Americas, but he did stumble upon them unintentionally as he was in fact looking for a route to India.
February 24th, 2008 at 3:42 pm
I think the clitoris should also be on there.
February 24th, 2008 at 3:46 pm
BTrout:
Unfortunately, some guys still haven’t found it!!!
February 24th, 2008 at 3:48 pm
OMG the pic for the popsicle. Are you sure that wasn’t for the Viagra? Fun list.
February 24th, 2008 at 3:52 pm
haha loving these comments
February 24th, 2008 at 4:32 pm
Angelina; hahaha, good one!
February 24th, 2008 at 4:38 pm
Angelina and Mom424: Not fair! (I have found it though
)
February 24th, 2008 at 4:39 pm
Csimmons: and you were greatly rewarded?
February 24th, 2008 at 4:58 pm
Ummmm,,,,, i was lying. Sorry!
February 24th, 2008 at 5:01 pm
actually that last comment was a lie. my brother typed it. and yes, i was rewarded!
February 24th, 2008 at 5:11 pm
for penicillin the person who discovered it was Dr.Cloromido Picado not fleming.he has records of using it between 1917 and 1927 way before fleming.
February 24th, 2008 at 5:21 pm
TicoTuanis: do you have a source for that in English? I can’t find him in any English language reference books.
February 24th, 2008 at 5:42 pm
I love the double entendres in the Viagra listing! “Hard working stiffs”? “Firm evidence”? Very nicely done!
February 24th, 2008 at 5:44 pm
Kiwiboi:
I think that picture used on the list was for humor purposes only:)
I completely agree with you, the rumor that aspartame causes cancer is completely that: a rumor.
For those who disagree…Someone asked that on Yahoo Answers and here was my answering–see the websites I quote as a resource is my answer doesn’t make you agree with me.
http://answers.yahoo.com/question/index?qid=20071205102019AAXmoPs
February 24th, 2008 at 6:21 pm
Great list but whatever happened to grammar?
February 24th, 2008 at 6:22 pm
matt:grammer is for wussys! LOL!
February 24th, 2008 at 6:38 pm
Post-it notes should be included,as the glue on the back was discovered accidentally.
Fire would definitely qualify!
#7 Another Kiwi: those are the four basic food groups!
February 24th, 2008 at 6:44 pm
I’d have to say the bedt for me is them ‘tater totz, they is real good. Those who eat them sure do got purdy mouths.
-Andrea Carlena Beauman
February 24th, 2008 at 6:44 pm
**BEST
-Andrea Carlena Beauman
February 24th, 2008 at 6:57 pm
Sorry but yes indeed Reagan was referred to as the Teflon President – he had the slaphappy luck of all the stupid things he did sliding right off of him and affecting someone else instead.
February 24th, 2008 at 8:07 pm
jfrater: i am advertising this site on my youube page, this should get you some more views!
my channel is Kissfan1267 in case you’re wondering
or just look for a vid called “side effects of cialis” then you’ll find my page!
February 24th, 2008 at 9:07 pm
Not to be too persnickety, but Dubya is technically not Jr.
Angelina, et al: too funny
[ some of us have, plus the advantages of knowing how to give a right proper foot rub ]
February 24th, 2008 at 9:07 pm
9. Chocolate Chip Cookies
“instead of patenting it and making billions”
Mrs. Wakefield could not patent the recipe because recipes are not patentable. That is why companies keep proprietary secrets.
February 24th, 2008 at 9:28 pm
the first guy taking chest pain medication that ended up with a raging hard on; i wonder what his excuse was to his wife.
February 24th, 2008 at 9:51 pm
What about gravity?? The whole isaac newton and the apple thing…
February 24th, 2008 at 10:21 pm
Uhh, the legend of Potato Chip and Cornelius Vanderbilt thing is bogus. I think I saw it on History Channel’s Modern Marvel (Salty Snack episode) a couple of weeks ago. I’m guessing you got this info from wikipedia’s “legend has it” or something like that. I think I’m gonna go fix it.
February 24th, 2008 at 10:24 pm
http://www.snopes.com/business/origins/chips.asp
February 25th, 2008 at 12:19 am
Lucy’s got that classic “You’ve got some ’splaining to do” look, very hilarious in the context of viagra. Well written list. Maybe room for a Top 15 here with some of the discoveries mentioned here.
If the chips story is real, I don’t think it qualifies as accidental. He intentionally cut potatoes extra thin and intentionally fried them to a crisp, hence, intentional equals not accidental.
February 25th, 2008 at 12:21 am
For some reason that picture of Lucille Ball creeps me out…but it’s a perfect picture for viagra haha
February 25th, 2008 at 12:57 am
Thanks all for the comments – I have updated the list with a few corrections
February 25th, 2008 at 1:42 am
Jamie, when u grow 50s, u will put viagra as no 1..LOL. It saves a lot of marriages!!
February 25th, 2008 at 2:48 am
haha, i work in a pharmacy and like clockwork, every guy comes in on fridays and saturdays picking up their viagra refills. Funny that it was discovered in wales, i gotta find a way to tease my boyfrind about that. He’s from wales.
Guided by God for the betterment of man, thats classic!
February 25th, 2008 at 3:01 am
Nice list! My favorite accident that wasn’t on this list has to be nachos, though. Love those things… so much…
February 25th, 2008 at 6:24 am
Did the fonts get smaller or is it just me?
February 25th, 2008 at 6:29 am
JwJwBean: they got a smidge smaller
February 25th, 2008 at 6:55 am
I think you messed up the pictures jamie, the popsicle picture definitely belongs in the viagra category.
Did someone mention clitoris? What’s that?
February 25th, 2008 at 1:58 pm
buclism: are you kidding me? in a mans terms its the hood of the vagina which makes her moan.
February 25th, 2008 at 2:07 pm
Csimmons: Haha….how old are you again? Have you even seen a real vagina in your life?
February 25th, 2008 at 5:54 pm
slickwilly: yes, on the internet.
February 25th, 2008 at 11:35 pm
Interesting list!
Is this list arranged in descending order? Penicillin is the biggest sale ever and Viagra is still the 10th because it is comparatively new?
February 26th, 2008 at 1:52 am
I agree #8 should be for viagra, too!!!!!!
#1 I guess Ricky had been working too hard (but not hard enough for Lucy) with the band or hangin with Fred too much on the golf course.
Doesn’t Crum(s) go together with Potato chips?
February 26th, 2008 at 9:01 am
What abt gravity? Does it not qualify? Althouh it wasnt like a discovery….I dunno…Im confused :s
February 26th, 2008 at 12:27 pm
“Second only to the political wrangling of President George Bush”
OK this was funny but kind of a cheap shot. Don’t you think?
I mean come on.
With an approval rating of 19% I would hardly call him a Teflon president.
Maybe more like a Velcro president would be more like it (another accidental discovery by the way)
We still have to be reminded that he doesn’t pronounce nuclear correctly.
By the way, I just heard Bush and his administration have given more than any other president (billions) to fight disease and poverty in Africa.
This is the kind of information that doesn’t seem to “stick” I guess because we are too worried about how he pronounces nuclear.
Sorry to go on like that but I wanted to get it off my chest .
Good List by the way.
February 26th, 2008 at 3:37 pm
In regards to the potato chip:
Why do you have a photo of a basket of “Pringles”.
Pringles must be sold as “Potato CRISPS”, not chips!
February 27th, 2008 at 3:46 pm
TDavis: I don’t care what the European Union declares – I do what I want and I liked that photo most
February 28th, 2008 at 9:11 pm
wasnt asprin also discovered by accident. if not uses for it are being discovered that way all the time. if it had been discovered in the last 10 years it would be costing us 20 dollars a pill.
February 29th, 2008 at 3:47 pm
goof_ball said: “Who ever thought you could make something extraordinary on accident.”
Does my son count?
March 1st, 2008 at 8:10 pm
The X-ray should definitely be included in this list.
March 3rd, 2008 at 11:37 am
Wish I could have myself another “Bicycle Day”. Ah, good times, good times. Although we called it “Watching July 4th fireworks in boat at night on a dark lake in the Adirondacks”.
Best trip EVER.
March 9th, 2008 at 11:07 am
One problem with #8, Frank epperson didn’t patent the popsicle. his son did, and named it the popsicle in his father’s honor. Although, when the elder epperson sold them, he did call the epsicles.
March 9th, 2008 at 11:20 am
Fluffnutter: I beg to differ – here is the timeline:
1905, 11 year old Frank Epperson left a mixture of powdered soda and water out on ice porch, which contained a stir stick.
1924, Frank Epperson applied for a patent for “frozen confectionery” called the Epsicle ice pop, which he re-named the Popsicle, allegedly at the instigation of his children.
1925, Epperson sold the Popsicle to the Joe Lowe Company of New York. Good Humor, a subsidiary of Unilever, now owns the rights.
Here is Epperson’s patent:
http://www.google.com/patents?id=HYBSAAAAEBAJ
March 10th, 2008 at 3:56 pm
I’m 37 and discovered the clitoris 2 years ago lol never too late. I’m hoping to discover something else before I’m old but if not that’ll do lol. Merthyr is just a little bit bigger than a village now and they are all hard as f**k, mad coincidence. I had a ear infection once so penicillin and asprin are my #2 and#3 you all know my number #1 lol….
May 16th, 2008 at 12:50 pm
Neat list–you might have added how scientists discovered the DNA double-helix . . .
July 8th, 2008 at 12:29 am
Staph isn’t the only cause of food poisoning and not all types of it cause food poisoning. There are about 30 species of Staphylococcus – most of them are quite harmless and live on your skin or up your nose (and other moist areas of the body
). Some strains of S. aureus can cause food poisoning but I don’t think it’s completely correct to say,
“In 1928, Scottish Scientist Sir Alexander Fleming was studying Staphylococcus – the bacteria that causes food poisoning. ”
- because it isn’t THE cause of food poisoning. There is more about S. aureus and Alexander Fleming’s dicovery of penicillin here:
http://www.lrb.co.uk/v27/n24/penn01_.html
I’m just arguing about semantics. Otherwise I really liked the list
July 9th, 2008 at 9:56 pm
#1: Cosmic Microwave Background
September 20th, 2008 at 3:27 am
this is unbelieve able thanks guys for all the help
November 10th, 2008 at 10:13 am
Amazing list! I really enjoy the comments, they’re so funny.
February 25th, 2009 at 7:23 pm
Great list, the picture for number 10 cracked me up!
April 12th, 2009 at 3:32 pm
Acesulfame-K, that is Acesulfame potassium, another artificial sweetener was also discovered accidentally. Two researchers were working on some research with chemicals. One asked the other to test the compound, the other though he asked him to taste it, and after he tasted it, it was found sweet. Surcralose was also found by accident.
Type Acesulfame-K, also Sucralose, on Wikipedia.org and read more.
June 9th, 2009 at 3:21 am
I know you have the microwave but for us students, it’s priceless.
September 20th, 2009 at 12:41 am
“second only to the political wrangling of President George Bush.”
Which are now third to the lies of Barack Obama.
Don’t like my comment? Then leave snotty little political comments out of the lists.
September 25th, 2009 at 7:10 am
Whenever Thomas Amusements, a travelling amusement park, comes to town, they always serve Saratoga Chips.
Still called that
October 22nd, 2009 at 3:02 pm
great list. W…. countries worst president ever.
oh why did he it have to be during my lifetime……..
October 27th, 2009 at 11:59 pm
Is it a sign that LSD was created on my birthday
October 29th, 2009 at 4:46 pm
mmmm brandy and cherry coke
yum
November 6th, 2009 at 8:12 am
To the author: Do you think it possible that you could put together a nice and useful list without making some snide, BDS (Bush Derangement Syndrome) comment such as that which you inserted into the Teflon description? Why not a comment about Clinton, AKA “Slick Willy”? Personally I think all politicians are ’slick’, which is how they manage to convince us they somehow have ‘the answers’ even though they aren’t smarter than us. Really, such snarky little comments degrade the quality of this entire list.
November 29th, 2009 at 8:42 am
In the Teflon story your cut at George Bush would have been more accurately told as “Slick Willy” Bill Clinton.
December 6th, 2009 at 9:20 am
frater your a horses behind to say that about george bush. you should have said it about slick willy. remember its dems who are the real turds in this country.
December 24th, 2009 at 11:21 pm
I’m surprised Post-it notes didn’t make the list.
p.s. the Bush remark was unnecessary.
January 19th, 2010 at 6:22 am
Accidental discoveries are cool, because ppl work hard at getting, let’s say, the cure for one thing and end up curing something else… It’s better than winding up with nothing.
February 5th, 2010 at 4:41 pm
Really? Had to throw in the remark about President Bush? Really?