Psychology is a relatively new science which gained popularity in the early 20th century with Wilhelm Wundt. In the zeal to learn about the human thought process and behavior, many early psychiatrists went too far with their experimentations, leading to stringent ethics codes and standards. Though these are highly unethical experiments, it should be mentioned that they did pave the way to induct our current ethical standards of experiments, and that should be seen as a positive. There is some crossover on this list with the Top 10 Evil Human Experiments. Three items from that list are reproduced here (items 8, 9, and 10) for the sake of completeness.

The Monster Study was a stuttering experiment on 22 orphan children in Davenport, Iowa, in 1939 conducted by Wendell Johnson at the University of Iowa. Johnson chose one of his graduate students, Mary Tudor, to conduct the experiment and he supervised her research. After placing the children in control and experimental groups, Tudor gave positive speech therapy to half of the children, praising the fluency of their speech, and negative speech therapy to the other half, belittling the children for every speech imperfection and telling them they were stutterers. Many of the normal speaking orphan children who received negative therapy in the experiment suffered negative psychological effects and some retained speech problems during the course of their life. Dubbed “The Monster Study” by some of Johnson’s peers who were horrified that he would experiment on orphan children to prove a theory, the experiment was kept hidden for fear Johnson’s reputation would be tarnished in the wake of human experiments conducted by the Nazis during World War II. The University of Iowa publicly apologized for the Monster Study in 2001.

South Africa’s apartheid army forced white lesbian and gay soldiers to undergo ‘sex-change’ operations in the 1970′s and the 1980′s, and submitted many to chemical castration, electric shock, and other unethical medical experiments. Although the exact number is not known, former apartheid army surgeons estimate that as many as 900 forced ‘sexual reassignment’ operations may have been performed between 1971 and 1989 at military hospitals, as part of a top-secret program to root out homosexuality from the service.
Army psychiatrists aided by chaplains aggressively ferreted out suspected homosexuals from the armed forces, sending them discretely to military psychiatric units, chiefly ward 22 of 1 Military Hospital at Voortrekkerhoogte, near Pretoria. Those who could not be ‘cured’ with drugs, aversion shock therapy, hormone treatment, and other radical ‘psychiatric’ means were chemically castrated or given sex-change operations.
Although several cases of lesbian soldiers abused have been documented so far—including one botched sex-change operation—most of the victims appear to have been young, 16 to 24-year-old white males drafted into the apartheid army.
Dr. Aubrey Levin (the head of the study) is now Clinical Professor in the Department of Psychiatry (Forensic Division) at the University of Calgary’s Medical School. He is also in private practice, as a member in good standing of the College of Physicians and Surgeons of Alberta.

This study was not necessarily unethical, but the results were disastrous, and its sheer infamy puts it on this list. Famed psychologist Philip Zimbardo led this experiment to examine that behavior of individuals when placed into roles of either prisoner or guard and the norms these individuals were expected to display.
Prisoners were put into a situation purposely meant to cause disorientation, degradation, and depersonalization. Guards were not given any specific directions or training on how to carry out their roles. Though at first, the students were unsure of how to carry out their roles, eventually they had no problem. The second day of the experiment invited a rebellion by the prisoners, which brought a severe response from the guards. Things only went downhill from there.
Guards implemented a privilege system meant to break solidarity between prisoners and create distrust between them. The guards became paranoid about the prisoners, believing they were out to get them. This caused the privilege system to be controlled in every aspect, even in the prisoners’ bodily functions. Prisoners began to experience emotional disturbances, depression, and learned helplessness. During this time, prisoners were visited by a prison chaplain. They identified themselves as numbers rather than their names, and when asked how they planned to leave the prison, prisoners were confused. They had completely assimilated into their roles.
Dr. Zimbardo ended the experiment after five days, when he realized just how real the prison had become to the subjects. Though the experiment lasted only a short time, the results are very telling. How quickly someone can abuse their control when put into the right circumstances. The scandal at Abu Ghraib that shocked the U.S. in 2004 is prime example of Zimbardo’s experiment findings.
While animal experimentation can be incredibly helpful in understanding man, and developing life saving drugs, there have been experiments which go well beyond the realms of ethics. The monkey drug trials of 1969 were one such case. In this experiment, a large group of monkeys and rats were trained to inject themselves with an assortment of drugs, including morphine, alcohol, codeine, cocaine, and amphetamines. Once the animals were capable of self-injecting, they were left to their own devices with a large supply of each drug.
The animals were so disturbed (as one would expect) that some tried so hard to escape that they broke their arms in the process. The monkeys taking cocaine suffered convulsions and in some cases tore off their own fingers (possible as a consequence of hallucinations), one monkey taking amphetamines tore all of the fur from his arm and abdomen, and in the case of cocaine and morphine combined, death would occur within 2 weeks.
The point of the experiment was simply to understand the effects of addiction and drug use; a point which, I think, most rational and ethical people would know did not require such horrendous treatment of animals.
In 1924, Carney Landis, a psychology graduate at the University of Minnesota developed an experiment to determine whether different emotions create facial expressions specific to that emotion. The aim of this experiment was to see if all people have a common expression when feeling disgust, shock, joy, and so on.
Most of the participants in the experiment were students. They were taken to a lab and their faces were painted with black lines, in order to study the movements of their facial muscles. They were then exposed to a variety of stimuli designed to create a strong reaction. As each person reacted, they were photographed by Landis. The subjects were made to smell ammonia, to look at pornography, and to put their hands into a bucket of frogs. But the controversy around this study was the final part of the test.
Participants were shown a live rat and given instructions to behead it. While all the participants were repelled by the idea, fully one third did it. The situation was made worse by the fact that most of the students had no idea how to perform this operation in a humane manner and the animals were forced to experience great suffering. For the one third who refused to perform the decapitation, Landis would pick up the knife and cut the animals head off for them.
The consequences of the study were actually more important for their evidence that people are willing to do almost anything when asked in a situation like this. The study did not prove that humans have a common set of unique facial expressions.

John Watson, father of behaviorism, was a psychologist who was apt to using orphans in his experiments. Watson wanted to test the idea of whether fear was innate or a conditioned response. Little Albert, the nickname given to the nine month old infant that Watson chose from a hospital, was exposed to a white rabbit, a white rat, a monkey, masks with and without hair, cotton wool, burning newspaper, and a miscellanea of other things for two months without any sort of conditioning. Then experiment began by placing Albert on a mattress in the middle of a room. A white laboratory rat was placed near Albert and he was allowed to play with it. At this point, the child showed no fear of the rat.
Then Watson would make a loud sound behind Albert’s back by striking a suspended steel bar with a hammer when the baby touched the rat. In these occasions, Little Albert cried and showed fear as he heard the noise. After this was done several times, Albert became very distressed when the rat was displayed. Albert had associated the white rat with the loud noise and was producing the fearful or emotional response of crying.
Little Albert started to generalize his fear response to anything fluffy or white (or both). The most unfortunate part of this experiment is that Little Albert was not desensitized to his fear. He left the hospital before Watson could do so.
In 1965, psychologists Mark Seligman and Steve Maier conducted an experiment in which three groups of dogs were placed in harnesses. Dogs from group one were released after a certain amount of time, with no harm done. Dogs from group two were paired up and leashed together, and one from each pair was given electrical shocks that could be ended by pressing a lever. Dogs from group three were also paired up and leashed together, one receiving shocks, but the shocks didn’t end when the lever was pressed. Shocks came randomly and seemed inevitable, which caused “learned helplessness,” the dogs assuming that nothing could be done about the shocks. The dogs in group three ended up displaying symptoms of clinical depression.
Later, group three dogs were placed in a box with by themselves. They were again shocked, but they could easily end the shocks by jumping out of the box. These dogs simply “gave up,” again displaying learned helplessness. The image above is a healthy pet dog in a science lab, not an animal used in experimentation.

The notorious Milgrim Study is one of the most well known of psychology experiments. Stanley Milgram, a social psychologist at Yale University, wanted to test obedience to authority. He set up an experiment with “teachers” who were the actual participants, and a “learner,” who was an actor. Both the teacher and the learner were told that the study was about memory and learning.
Both the learner and the teacher received slips that they were told were given to them randomly, when in fact, both had been given slips that read “teacher.” The actor claimed to receive a “learner” slip, so the teacher was deceived. Both were separated into separate rooms and could only hear each other. The teacher read a pair of words, following by four possible answers to the question. If the learner was incorrect with his answer, the teacher was to administer a shock with voltage that increased with every wrong answer. If correct, there would be no shock, and the teacher would advance to the next question.
In reality, no one was being shocked. A tape recorder with pre-recorded screams was hooked up to play each time the teacher administered a shock. When the shocks got to a higher voltage, the actor/learner would bang on the wall and ask the teacher to stop. Eventually all screams and banging would stop and silence would ensue. This was the point when many of the teachers exhibited extreme distress and would ask to stop the experiment. Some questioned the experiment, but many were encouraged to go on and told they would not be responsible for any results.
If at any time the subject indicated his desire to halt the experiment, he was told by the experimenter, Please continue. The experiment requires that you continue. It is absolutely essential that you continue. You have no other choice, you must go on. If after all four orders the teacher still wished to stop the experiment, it was ended. Only 14 out of 40 teachers halted the experiment before administering a 450 volt shock, though every participant questioned the experiment, and no teacher firmly refused to stop the shocks before 300 volts.
In 1981, Tom Peters and Robert H. Waterman Jr. wrote that the Milgram Experiment and the later Stanford prison experiment were frightening in their implications about the danger lurking in human nature’s dark side.

Dr. Harry Harlow was an unsympathetic person, using terms like the “rape rack” and “iron maiden” in his experiments. He is most well-known for the experiments he conducted on rhesus monkeys concerning social isolation. Dr. Harlow took infant rhesus monkeys who had already bonded with their mothers and placed them in a stainless steel vertical chamber device alone with no contact in order to sever those bonds. They were kept in the chambers for up to one year. Many of these monkeys came out of the chamber psychotic, and many did not recover. Dr. Harlow concluded that even a happy, normal childhood was no defense against depression, while science writer Deborah Blum called these, “common sense results.”
Gene Sackett of the University of Washington in Seattle, one of Harlow’s doctoral students, stated he believes the animal liberation movement in the U.S. was born as a result of Harlow’s experiments. William Mason, one of Harlow’s students, said that Harlow “kept this going to the point where it was clear to many people that the work was really violating ordinary sensibilities, that anybody with respect for life or people would find this offensive. It’s as if he sat down and said, ‘I’m only going to be around another ten years. What I’d like to do, then, is leave a great big mess behind.’ If that was his aim, he did a perfect job.”
In 1965, a baby boy was born in Canada named David Reimer. At eight months old, he was brought in for a standard procedure: circumcision. Unfortunately, during the process his penis was burned off. This was due to the physicians using an electrocautery needle instead of a standard scalpel. When the parents visited psychologist John Money, he suggested a simple solution to a very complicated problem: a sex change. His parents were distraught about the situation, but they eventually agreed to the procedure. They didn’t know that the doctor’s true intentions were to prove that nurture, not nature, determined gender identity. For his own selfish gain, he decided to use David as his own private case study.
David, now Brenda, had a constructed vagina and was given hormonal supplements. Dr. Money called the experiment a success, neglecting to report the negative effects of Brenda’s surgery. She acted very much like a stereotypical boy and had conflicting and confusing feelings about an array of topics. Worst of all, her parents did not inform her of the horrific accident as an infant. This caused a devastating tremor through the family. Brenda’s mother was suicidal, her father was alcoholic, and her brother was severely depressed.
Finally, Brenda’s parents gave her the news of her true gender when she was fourteen years old. Brenda decided to become David again, stopped taking estrogen, and had a penis reconstructed. Dr. Money reported no further results beyond insisting that the experiment had been a success, leaving out many details of David’s obvious struggle with gender identity. At the age of 38, David committed suicide.
This article is licensed under the GFDL because it contains quotations from Wikipedia.
Contributor: Maggie
























#1 is *****ed up. Also, I heard he had a twin brother.
False. He did have a brother, but not a twin.
he did have a twin
yeh i agree he did have a twin
even i have a twin
who likes my twin
David Reimer was actually born Bruce and he did have a twin.
You’re thinking of the “Law & Order: SVU” episode that was based on this case. In that episode the character modeled after David had a twin brother.
He did have a twin. Read the book: as nature made him.
Substantial overlap with this list
http://listverse.com/crime/top-10-evil-human-expe…
it’s mentioned in the description.
nice list
gdgd
bad
meh!
Mister Frater you are sapping my moral. Enough heavy duty lists already. Gimme something lighthearted and fun. Please sir.
emmstein- I believe he was.
glittershrooms: from your comment should I presume you don’t consider ethics important in experimentation?
glittershrooms: okay – tomorrow I will do a happy list
His birth name was Bruce, and his twin brother was Brian.
his birth name was jim,and his twin brother was retarded cripple
glittershrooms: what subject do you want me to cover?
Jamie, ethics are really important to me. It is beside the point. When I log on, I expect to be entertained and not depressed. Sorry but I guess I only enjoy the fun lists. I apologize.
Jamie dear, you are doing a great job. Do not listen to me, I’m a lil grumpy.
flowers for algernon could be a bonus, eventhough its fiction
Yes that was very Unethical even though it was false
I’m depressed.
interesting list
but you forgot one the most controvertial ones:
project MKULTRA
http://en.wikipedia.org/wiki/Project_MKULTRA
but I don’t know if it belongs here because seems more a psychiatric than psychological experiment
okay – maybe sad lists and mondays don’t mix well.
Stanford Prison Experiment lead to the german Das Experiment movie by Oliver Hirschbiegel. A good one to be seen
JB: that is on the list I mention in the opening statement of this list.
JB: das experiment is a brilliant film – I totally agree!
(about #1)
Didn’t the Reimer’s seek the opinion(s) of other professionals? Didn’t they consider alternatives, like reconstruct the penis? I think it’s ridiculous that they went along with the ***** change.
I hope my comment makes sense. My nerves are shot because I’m sitting here with my very sick 19 year old cat.
cool
i am cool
drogo – I agree completely but from what I read about the case the parents were disfunctional alcoholics (some alchies are functional) and the doctor had them convinced that gender reassignment was the right (and only viable) choice. Despite the trauma the poor boy suffered in puberty, the doctor considered his “experiment” a success and believed he proved that nurture determined gender, not nature.
it’s horrific to see what lengths people would go through to get their points across.. cruelty to all livings things should be absolutely condemned. Most of the times these experiments don’t even produce a conclusive result, all they leave behind is a lasting effect on the psychology of the subjects.
I think David Reimer’s story was used in one of ‘Law & Order: SVU’s episodes.
uups!
I saw it right now,
thanks
This lists seems familiar… is there one like it already?
David Reimer and his twin both went in for circumcision; because David’s was botched, his brother’s was never done. Dr. Money was considered to be an expert in his field, and the parents were probably intimidated by him and put their whole faith in him. Years ago, people didn’t tend to question professionals. David was raised in dresses and hated them; it was only when Dr. Money wanted to perform a second surgery that David severely protested and his parents finally broke down and told him. He immediately began dressing as a male, and eventually had reconstruction. He did marry but the depression and anger were too great. There’s much more to the story, but it’s depressing – a book was published on his interviews.
great list :] though id just like to mention that after milgrams study, though it was unethical, the participants were introduced to the ‘victim’ and told that they were fine and their behaviour was normal, so that they didnt leave scarred for life. Id hate to be in their position and never knowing if id killed someone or not!
I love the list. It makes me a little sad because it reminds me that there are monsters out there that look like normal people. Our government is full of them. I also wonder sometimes if we ever unknowingly reap any benefits from these “experiments”. Not just stricter codes of ethics, but helpful treatmnts or medicines.
I’ve never thought the Milgram experiment was THAT unethical…. but I don’t know what the impact on those studied was. Fascinating experiment all the same, as was the Stanford one (the Stanford one was pretty unbelievable by the end of it)!
Very Interesting.
Surprise the Tuskeegee Syphilis Experiments wasn’t on the list.
Poor,poor, poor David.
mcsquida: you need to watch the video to get a grasp for just how distressing the screaming and wall-banging was. it was pretty brutal.
And I thought medical ethics were bad today…..
number 1 is just pure evil and selfishness.. after i finished reading it my face was like =.=” its amazing what goes on people’s minds when they follow through their dark side..
for the milgram study, go to google video and type in “milgram study”. it is the second choice.
they have the entire 45 min video.
I think this list is in itself a cruel psychological experiment to see how depressed a person can get about humanity.
NestorV: The Tuskegee Syphilis Experiments were physical, not psychological.
On the Stanford Prison Experiment: The official website, http://www.prisonexp.org/ , really helps show how it all went. Even the researchers got drawn into it. They worked to avert a planned ‘breakout’, forgetting that it was all fictional and that they were observers, not wardens. It was scheduled to last two weeks, but was, fortunately, cut short.
CRAZY, I’ve actually met Dr. Levin from #9…I used to work for a financial advisor, and Aubrey and his wife were my boss’s clients. He was very polite, well-spoken, and extremely wealthy…I had no idea he would be capable of something that horrendous.
Just Google his name and see what pops up. Kinda scary.
wow, what an amazing intresting list. Very Disturbing stuff, but very interesting
I have a degree in psychology and have heard of most of these before. I do want to say that in order to conduct ‘studies,’ or ‘experiments’ now, you have to go through a lengthy application process, which is approved or denied by a board. These stories are unfortunate, how someone who studies the human mind can subject others or animals to these terrors is beyond me. The prison study is the most fascinating, it goes hand in hand with # 3. Generally, people are very obedient and will follow instructions and do what they are told. The human mind is more suggestible than a lot of people realize.
I’m not a big mistake pointer-outter but on # 6 it said 1/3 did it and then said 1/3 refused and had it done for them..or maybe I’m reading it wrong.
At any rate, this was a really interesting list. The animal ones were really sad.
There was an episode of law and order that is like #1 It’s terrible what some people call a success.
Milgrams study is not unethical, the participants could stop at any time. The first is very twisted but it did seem to work until he hit puberty.
i get so curious and fascinated by lists like this. Excellent job!!!
Number 9…that’s truly an abomination. Of course that’s probably because it hits too close to home for me. I don’t even know what I would do if my command one day told me I suddenly had to be a chick…
yay! nature 1 nurture 0
Nice list again but It would be nice to lift the gloomy clouds a wee bit now and again.
#24 deepthinker is correct – a saw a web site not so long ago about human torture and most of them are on their site.
Wow, this is an intense list. It was hard to read a few of those descriptions all the way through.
I do think #8 and #3 were important in regards to the exposure of human/group mentality etc. I don’t think the experiments in themselves were necessarily unethical.
on #1, unless my eyes just skipped it, you forgot an important fact. David had an identical twin brother. The psychiatrist wanted to conduct a Nature vs Nurture experiment. He had wanted to know if he could raise two people who were exactly alike, in very different ways. Hence, raise one brother as a boy, and raise one as a girl, and see what took over, nature or nurture. His theory was that nurture would overcome nature. All throughout Davids childhood, he would try to convince him to undergo another ***** change operation (either the first one wasn’t performed, or it was botched, I don’t remember which) by telling him his genitals were deformed, and they could fix it with reconstructive surgery so he would look just like all the other girls. He even brought tran*****uals into the therapy sessions to tell him how much better he would feel after he had surgery, since he would then look like all the other girls. David never wanted further surgery to make his “vagina” look normal, which was a great frustration to the doctor.
The experiment wasn’t about raising a boy as a girl, and seeing if it would be a success, it was about Nature vs Nurture. He wanted to prove that even though someone was born a boy, they could be raised as a girl, and lead a very healthy, productive feminine life, and never know the difference, because gender was not determined by whether someone was born with a penis or vagina, but by the way they were raised. He needed identical twins for the experiment though, and can you imagine how overjoyed he was when he heard of the botched circumcision, and he finally had a chance to carry out his “experiment”?
His experiment wouldn’t work if David was a single child and not a twin, because David might have grown up to be a tran*****ual anyway, so he needed a set of twins, because of course, twins are exactly alike, and if one is straight, the other will be straight to. He needed to make sure that David being a girl was a product of how he was raised, and not something that would have happened anyway. So he had to do his experiment with twins.
I think it’s very sad that even after the experiment failed, the doctor still published it as a success, denying that he was wrong in any way at all. He felt absolutely no remorse for what he did to that family.
neflite—you summed it up perfectly!
Fascinating. The only thing that really bottles the mind is the fact that the test subjects in some experiments are aware and can choose to react anyway to the experiment, rather it be totally irrelevant or not. For example, if one were being shocked by volts of electricity to enforce behavior on a misbehaving subject, but the misbehaving subject was aware of the purpose of the experiment and chose to act a certain way that wasn’t his/her true reaction….again…fascinating.
Oh! I haven’t read through it all yet – but I just love reading the strange experiments people put themselves through and such. Humans are strange…
Maggie, although I’d read about many of these “tests”, a few were new to me. All were atrocious.
That mankind can perform these kinds of horrors on other beings, both human and nonhuman, for reasons of psychological testing (usually where the answer is known beforehand), is outrageous.
As you all know, I support animal testing when it comes to new drugs, but this is completely different. This is just horrendous.
Completely different? Perhaps you'd like to be tested on some day? No? Why not? Oh you would not like to suffer? Threat not your ignorance and evil is normal.
Sandra: I disagree with your comment “he needed a set of twins, because of course, twins are exactly alike, and if one is straight, the other will be straight to.” I know a set of identical twins, one who is straight (and getting married soon) and the other a lesbian. I don’t think being a twin pre-determines one’s personality and *****ual preference.
These are a little out of order. #9 and #10 s/be higher, they are very disturbing. #8 and #3?…meh, I’ve heard o’ worse. #7 and #2 s/change places. Physical torture of an animal is just as bad as physical torture of a human. They feel physical pain the same as we do. I doubt they feel psychological pain as much as we do,..they’re incapable of abstract thought. #6 is about where it s/be. #5 sounds like “A Clockwork Orange.” #4, learned helplessness,…sounds like what I was taught in Catholic school,…I can relate to that third group of dogs. #1? very appropriate choice. You were correct to leave out “The Tuskeegee experiment.” It does not belong on this list, unless you want to replace #2 with it. There’s an urban myth that those men were INJECTED with syphillis, in which case it s/be #1 here. The fact is, they already had it, but were left untreated and told they were being treated. That’s a sick experiment but it would have been 1000 times worse if HEALTHY men were injected with it outside of their knowledge. Please don’t insult anyone’s intelligence, including your own, by asking what makes the two scenarios are different.
Brittany112: despite what you’ve heard, being born gay has never been sufficiently nor necessarily proven scientifically but only been said in theory to feed a much asked question. Twins are exactly alike, even their DNA.
Brittany– My comment about the twins was not a fact. It was the doctors belief that twins were alike. Maybe i should have added that somewhere in my comment. Sorry!!I was trying to show how stupid the doctor was, and ended up making MYSELF look ignorant.
Were any of these so called doctors arrested or punished in some way?
I hope, but I don't think so. I was SHOCKED to read that Aubrey Levin was living a normal life after what he did, and espacially that he could still practice medicine !
In 2010, Levin was accused by one of his patients of *****ual assault. Prosecutors have found many other patients with complaints, and only a few weeks ago (July 5, 2011) he was ordered to stand trial. He is currently prevented from practicing.
Those Canadians . . .
Some of those are effed up.
I don’t understand how some people can be so SICK.
Number 4 and 2 are the worst I think. I love animals =[