Psychology is a relatively new science which gained popularity in the early 20th century with Wilhelm Wundt. In the zeal to learn about the human thought process and behavior, many early psychiatrists went too far with their experimentations, leading to stringent ethics codes and standards. Though these are highly unethical experiments, it should be mentioned that they did pave the way to induct our current ethical standards of experiments, and that should be seen as a positive. There is some crossover on this list with the Top 10 Evil Human Experiments. Three items from that list are reproduced here (items 8, 9, and 10) for the sake of completeness.

The Monster Study was a stuttering experiment on 22 orphan children in Davenport, Iowa, in 1939 conducted by Wendell Johnson at the University of Iowa. Johnson chose one of his graduate students, Mary Tudor, to conduct the experiment and he supervised her research. After placing the children in control and experimental groups, Tudor gave positive speech therapy to half of the children, praising the fluency of their speech, and negative speech therapy to the other half, belittling the children for every speech imperfection and telling them they were stutterers. Many of the normal speaking orphan children who received negative therapy in the experiment suffered negative psychological effects and some retained speech problems during the course of their life. Dubbed “The Monster Study” by some of Johnson’s peers who were horrified that he would experiment on orphan children to prove a theory, the experiment was kept hidden for fear Johnson’s reputation would be tarnished in the wake of human experiments conducted by the Nazis during World War II. The University of Iowa publicly apologized for the Monster Study in 2001.

South Africa’s apartheid army forced white lesbian and gay soldiers to undergo ‘sex-change’ operations in the 1970′s and the 1980′s, and submitted many to chemical castration, electric shock, and other unethical medical experiments. Although the exact number is not known, former apartheid army surgeons estimate that as many as 900 forced ‘sexual reassignment’ operations may have been performed between 1971 and 1989 at military hospitals, as part of a top-secret program to root out homosexuality from the service.
Army psychiatrists aided by chaplains aggressively ferreted out suspected homosexuals from the armed forces, sending them discretely to military psychiatric units, chiefly ward 22 of 1 Military Hospital at Voortrekkerhoogte, near Pretoria. Those who could not be ‘cured’ with drugs, aversion shock therapy, hormone treatment, and other radical ‘psychiatric’ means were chemically castrated or given sex-change operations.
Although several cases of lesbian soldiers abused have been documented so far—including one botched sex-change operation—most of the victims appear to have been young, 16 to 24-year-old white males drafted into the apartheid army.
Dr. Aubrey Levin (the head of the study) is now Clinical Professor in the Department of Psychiatry (Forensic Division) at the University of Calgary’s Medical School. He is also in private practice, as a member in good standing of the College of Physicians and Surgeons of Alberta.

This study was not necessarily unethical, but the results were disastrous, and its sheer infamy puts it on this list. Famed psychologist Philip Zimbardo led this experiment to examine that behavior of individuals when placed into roles of either prisoner or guard and the norms these individuals were expected to display.
Prisoners were put into a situation purposely meant to cause disorientation, degradation, and depersonalization. Guards were not given any specific directions or training on how to carry out their roles. Though at first, the students were unsure of how to carry out their roles, eventually they had no problem. The second day of the experiment invited a rebellion by the prisoners, which brought a severe response from the guards. Things only went downhill from there.
Guards implemented a privilege system meant to break solidarity between prisoners and create distrust between them. The guards became paranoid about the prisoners, believing they were out to get them. This caused the privilege system to be controlled in every aspect, even in the prisoners’ bodily functions. Prisoners began to experience emotional disturbances, depression, and learned helplessness. During this time, prisoners were visited by a prison chaplain. They identified themselves as numbers rather than their names, and when asked how they planned to leave the prison, prisoners were confused. They had completely assimilated into their roles.
Dr. Zimbardo ended the experiment after five days, when he realized just how real the prison had become to the subjects. Though the experiment lasted only a short time, the results are very telling. How quickly someone can abuse their control when put into the right circumstances. The scandal at Abu Ghraib that shocked the U.S. in 2004 is prime example of Zimbardo’s experiment findings.
While animal experimentation can be incredibly helpful in understanding man, and developing life saving drugs, there have been experiments which go well beyond the realms of ethics. The monkey drug trials of 1969 were one such case. In this experiment, a large group of monkeys and rats were trained to inject themselves with an assortment of drugs, including morphine, alcohol, codeine, cocaine, and amphetamines. Once the animals were capable of self-injecting, they were left to their own devices with a large supply of each drug.
The animals were so disturbed (as one would expect) that some tried so hard to escape that they broke their arms in the process. The monkeys taking cocaine suffered convulsions and in some cases tore off their own fingers (possible as a consequence of hallucinations), one monkey taking amphetamines tore all of the fur from his arm and abdomen, and in the case of cocaine and morphine combined, death would occur within 2 weeks.
The point of the experiment was simply to understand the effects of addiction and drug use; a point which, I think, most rational and ethical people would know did not require such horrendous treatment of animals.
In 1924, Carney Landis, a psychology graduate at the University of Minnesota developed an experiment to determine whether different emotions create facial expressions specific to that emotion. The aim of this experiment was to see if all people have a common expression when feeling disgust, shock, joy, and so on.
Most of the participants in the experiment were students. They were taken to a lab and their faces were painted with black lines, in order to study the movements of their facial muscles. They were then exposed to a variety of stimuli designed to create a strong reaction. As each person reacted, they were photographed by Landis. The subjects were made to smell ammonia, to look at pornography, and to put their hands into a bucket of frogs. But the controversy around this study was the final part of the test.
Participants were shown a live rat and given instructions to behead it. While all the participants were repelled by the idea, fully one third did it. The situation was made worse by the fact that most of the students had no idea how to perform this operation in a humane manner and the animals were forced to experience great suffering. For the one third who refused to perform the decapitation, Landis would pick up the knife and cut the animals head off for them.
The consequences of the study were actually more important for their evidence that people are willing to do almost anything when asked in a situation like this. The study did not prove that humans have a common set of unique facial expressions.

John Watson, father of behaviorism, was a psychologist who was apt to using orphans in his experiments. Watson wanted to test the idea of whether fear was innate or a conditioned response. Little Albert, the nickname given to the nine month old infant that Watson chose from a hospital, was exposed to a white rabbit, a white rat, a monkey, masks with and without hair, cotton wool, burning newspaper, and a miscellanea of other things for two months without any sort of conditioning. Then experiment began by placing Albert on a mattress in the middle of a room. A white laboratory rat was placed near Albert and he was allowed to play with it. At this point, the child showed no fear of the rat.
Then Watson would make a loud sound behind Albert’s back by striking a suspended steel bar with a hammer when the baby touched the rat. In these occasions, Little Albert cried and showed fear as he heard the noise. After this was done several times, Albert became very distressed when the rat was displayed. Albert had associated the white rat with the loud noise and was producing the fearful or emotional response of crying.
Little Albert started to generalize his fear response to anything fluffy or white (or both). The most unfortunate part of this experiment is that Little Albert was not desensitized to his fear. He left the hospital before Watson could do so.
In 1965, psychologists Mark Seligman and Steve Maier conducted an experiment in which three groups of dogs were placed in harnesses. Dogs from group one were released after a certain amount of time, with no harm done. Dogs from group two were paired up and leashed together, and one from each pair was given electrical shocks that could be ended by pressing a lever. Dogs from group three were also paired up and leashed together, one receiving shocks, but the shocks didn’t end when the lever was pressed. Shocks came randomly and seemed inevitable, which caused “learned helplessness,” the dogs assuming that nothing could be done about the shocks. The dogs in group three ended up displaying symptoms of clinical depression.
Later, group three dogs were placed in a box with by themselves. They were again shocked, but they could easily end the shocks by jumping out of the box. These dogs simply “gave up,” again displaying learned helplessness. The image above is a healthy pet dog in a science lab, not an animal used in experimentation.

The notorious Milgrim Study is one of the most well known of psychology experiments. Stanley Milgram, a social psychologist at Yale University, wanted to test obedience to authority. He set up an experiment with “teachers” who were the actual participants, and a “learner,” who was an actor. Both the teacher and the learner were told that the study was about memory and learning.
Both the learner and the teacher received slips that they were told were given to them randomly, when in fact, both had been given slips that read “teacher.” The actor claimed to receive a “learner” slip, so the teacher was deceived. Both were separated into separate rooms and could only hear each other. The teacher read a pair of words, following by four possible answers to the question. If the learner was incorrect with his answer, the teacher was to administer a shock with voltage that increased with every wrong answer. If correct, there would be no shock, and the teacher would advance to the next question.
In reality, no one was being shocked. A tape recorder with pre-recorded screams was hooked up to play each time the teacher administered a shock. When the shocks got to a higher voltage, the actor/learner would bang on the wall and ask the teacher to stop. Eventually all screams and banging would stop and silence would ensue. This was the point when many of the teachers exhibited extreme distress and would ask to stop the experiment. Some questioned the experiment, but many were encouraged to go on and told they would not be responsible for any results.
If at any time the subject indicated his desire to halt the experiment, he was told by the experimenter, Please continue. The experiment requires that you continue. It is absolutely essential that you continue. You have no other choice, you must go on. If after all four orders the teacher still wished to stop the experiment, it was ended. Only 14 out of 40 teachers halted the experiment before administering a 450 volt shock, though every participant questioned the experiment, and no teacher firmly refused to stop the shocks before 300 volts.
In 1981, Tom Peters and Robert H. Waterman Jr. wrote that the Milgram Experiment and the later Stanford prison experiment were frightening in their implications about the danger lurking in human nature’s dark side.

Dr. Harry Harlow was an unsympathetic person, using terms like the “rape rack” and “iron maiden” in his experiments. He is most well-known for the experiments he conducted on rhesus monkeys concerning social isolation. Dr. Harlow took infant rhesus monkeys who had already bonded with their mothers and placed them in a stainless steel vertical chamber device alone with no contact in order to sever those bonds. They were kept in the chambers for up to one year. Many of these monkeys came out of the chamber psychotic, and many did not recover. Dr. Harlow concluded that even a happy, normal childhood was no defense against depression, while science writer Deborah Blum called these, “common sense results.”
Gene Sackett of the University of Washington in Seattle, one of Harlow’s doctoral students, stated he believes the animal liberation movement in the U.S. was born as a result of Harlow’s experiments. William Mason, one of Harlow’s students, said that Harlow “kept this going to the point where it was clear to many people that the work was really violating ordinary sensibilities, that anybody with respect for life or people would find this offensive. It’s as if he sat down and said, ‘I’m only going to be around another ten years. What I’d like to do, then, is leave a great big mess behind.’ If that was his aim, he did a perfect job.”
In 1965, a baby boy was born in Canada named David Reimer. At eight months old, he was brought in for a standard procedure: circumcision. Unfortunately, during the process his penis was burned off. This was due to the physicians using an electrocautery needle instead of a standard scalpel. When the parents visited psychologist John Money, he suggested a simple solution to a very complicated problem: a sex change. His parents were distraught about the situation, but they eventually agreed to the procedure. They didn’t know that the doctor’s true intentions were to prove that nurture, not nature, determined gender identity. For his own selfish gain, he decided to use David as his own private case study.
David, now Brenda, had a constructed vagina and was given hormonal supplements. Dr. Money called the experiment a success, neglecting to report the negative effects of Brenda’s surgery. She acted very much like a stereotypical boy and had conflicting and confusing feelings about an array of topics. Worst of all, her parents did not inform her of the horrific accident as an infant. This caused a devastating tremor through the family. Brenda’s mother was suicidal, her father was alcoholic, and her brother was severely depressed.
Finally, Brenda’s parents gave her the news of her true gender when she was fourteen years old. Brenda decided to become David again, stopped taking estrogen, and had a penis reconstructed. Dr. Money reported no further results beyond insisting that the experiment had been a success, leaving out many details of David’s obvious struggle with gender identity. At the age of 38, David committed suicide.
This article is licensed under the GFDL because it contains quotations from Wikipedia.
Contributor: Maggie
























About #1, if anybody wants the whole story along with photos, a book titled “As nature made him” by John Colapinto has all the details. I read that book and must say, there are pages that could make you cry. Let’s all be happy that we don’t have to go through what David had.
In #6- maybe I’m just not seeing it, but what did the other “one third” do? I only see two groups of “one thirds” regarding the rat
this list makes me sad
Just been reading the “Top 10 Moral Dilemmas” list and I think it makes a good companion list to the whole question of ethics and ethical decisions.
It’s enough to make you go cross-eyed really, if you think about things too much
Who’s the guy on the David Reimer item?
I knew you’d include the guard and prisoner thing- it’s so famous!
I’m surprised no one caught the error in the first paragraph. I know it’s a technicality and all, but Wundt “officially” founded psychology in 1879, not the early 20th century.
Also, a note on Harlow…The photos are from a more ethical experiment of his, where he took infant monkeys before they had bonded to their birth mothers, and tested to see which artificial surrogate mother they would prefer to bond with…a cloth covered one, or a wire one. Even when only the wire one provided milk, the monkeys would go over to them only to feed, and then return to the cloth mother.
I don’t always trust as much as you believe
The day after I read this,
we had a true or false test in my psychology class to test our knowledge.
and one of the questions was something alone the lines of,
“the majority of people would administer fatal electric shocks if told to do so”
i was the only person that put true :].
haha, listverse helps me pass class.
They may be “unethical,” but I believe we learn things we would never have known otherwise. Can you think of a humane way to do the nature vs. nurture on raising as a male or female? Or if someone will kill if an authority figure presides over them? It may be unethical, but it gets results.
The Well of Despair is weird.
For reference, the “rape rack” was a device that Harry invented in which he would set up a female monkey to be impregnanted and then see how she would behave to her offspring.
Raldan- so it gets results, and that means it okay to do? So with that logic, as long as anything is productive, it doesn’t matter who or what suffers in the process? Plan on voting McCain in November?
I would like to comment on the The Aversion Project. I was in the South African National Army and did my basic training in 1987. Most of my friends in the army were gay. I myself experimented with lesbian ***** and was caught and punished, but never have I ever heard about the things you say here. I contacted some of my friends who worked in 1 Military Hospital in Pretoria and they are not aware of it either. So I would love to know where this story originate from.
I’m not saying its not true, but it must have been top secret then and only for a selected few. Most of the gay men I knew ended up sjefs or medics.
I guess I was luck when I volunteered as a test subject that they didn’t do any wacko experiments on me.
What I did was a simple evaluation. They used a number instead of my name. Basically I portrayed(so to speak) a person whose mental status needed to be evaluated to see if a mental health issue contributed to them being involved in a crime, or being homeless, etc.
You need to refine this list. It confuses case studies with experiments [a very big distinction in psychology]. It also confuses psychologists with psychiatrists. And, it is poorly informed. Take for example, the learned helplessness studies. Are you aware that much of modern cardiology is based on dog studies, because the dog heart is so similar to that of humans? Each and every one of those animals are purchased from dog pounds and die as a result of the experiments.
Also, since you are mixing psychiatry and psychology, I would suggest you include frontal leucotomy (known as lobotomy) for which Moniz won a Nobel prize in 1949.
i feel so bad for brenda/david. his parents were *****s. and i hope hes happy now.
Uh, Barbie…David’s dead. He’s not feeling much of anything right now.
psychology in the early part of last century shows why the medical community needs to be regulated, they have no ethics where life is concerned and is why the new field of genetic manipulation needs to be regulated heavily.
I fail to see the direct link between the field of Psychology of the nineteenth and twentieth centuries, and field of genetics in the twenty-first century.
In fact, there is no link between Psychology and genetics at all.
If your argument, i dunno, is that of medical regulation, well, that already exists.
Basing your argument on a different field in a different century, is nonsense. No one could disagree that genetic manipulation, by which I can almost deduce you are referring to cloning or stem cell research (your sentence is unclear), requires oversight, but that oversight *HAS* to be done by the medical community, not the government.
Whoa, this is interesting, but pretty disturbing…
This is why there are now ethics boards that oversee research … what is somewhat horrifying is that people on their own couldn’t see how horribly inhumane and unethical they were being. People actually need an ethics board to let them know that physical and psychological torture may be a tad unethical.
These experiments are horrific!
Especially the ones done to animals. They aren’t able to speak up for themselves! That is just CRUEL. I felt a mix of emotions after reading these articles. Anger and Sadness were the main two. The poor dogs, monkeys, rats, and other animals being used for NO reason. Information and new research CAN be done without animal testing. It is unethical. Animals (and humans for that matter) weren’t put on this earth to be harmed on purpose, or used for scientific data that will eventually lead to their death (Ex: David or “Brenda.”)!
Davids/Brendas parents wanted the best for him at a time when not a lot was known about the psychological / sociological development of gender. I don’t think they were ‘*****s’ at all, they have suffered terribly. I saw a documentary about it and it showed him living relatively happily as a guy with a partner and looking after some kids. Sad to learn it got too much for him.
The Milgram experiment is unethical on so many levels, not least being deception. If you read more into it you will understand how distressing it is. Modern psychology guidelines practice protection for participants which means every participant should leave a psychological experiment as they entered it, which I doubt very much these people did.
The thing is most of these experiments were done before ethical guidelines were introduced. If Zimbardo tried to do this again now he’d probably be put in prison. (a real one
)
Just to let you know, http://www.soweirdo.com/2008/11/most-unethical-experiments.html ripped this list off for their website.
*Robert Plant*
DOES ANYONE REMEMBER THE TUSKEGEE EXPERIMENTS?!
David’s birth name was Brian, not David.
Very scary. I hope to go into the Phychology field when i grow up.. but nothing even close to this. This is why i am a vegitarian. I feel so bad for David, he must have been confused his whole life and the doctors just sat back and said ‘hmm.. that is interesting’ Personally i would sew if a doctor compleatly burned off my sons private parts. And taking an orphan and telling them how bad they are at talking… how horrible. taking a child in general and saying something like that.. or making them scared of anything white and soft how could someone do that? and the adults in this situation.. decapitating a rat or… letting shock happen (even though it was fake) it makes me think would i do that? ofcourse now i say no i would never do that.. but i bet those people would be thinking that too before it happened.. what made them keep going. even though they heard the screams and banging why didnt they just say enough and be done with it? its amazing how the human mind works.
I think you left off the Tuskeegee experiments! Those were horrid!!
WOW. i didnt know that psychology and specially psychologists can turn to be so sadistic. these experiments truly unveil the darker side of curiosity but what is worse- the darker side of human nature.
number 1 tho got really f**k up.i wonder what happened to the psychologist. what a name Mr Money. wonder if he commited suicide too. but for the last 5 or so, they have been published and recognized for their findings all over psych text books, wonder why the where put on this outrageous list
I find these kinds of experiments, though sadistic, extremely fascinating. If anyone is interested in more experiments like these, there is a book called ‘Elephants on Acid’ and it gives detailed descriptions of unethical experiments. I highly recommend it.
David/Brenda how very,very sad no wonder the poor man killed himself what a messed up life he had. shame on the parents who allowed this to happen.
I don’t think number 10 is that bad. If anything, it proves that parents can leave negative psychological and physical (speech) marks just by belittling their children.
So, parents, don’t belittle your children.
As to number 1: Why couldn’t the penis be reconstructed when it was first burned??? What the heck!
Its very telling how when not supervised, and without retrictions, professionals can overstep their boundaries. This is tantamount, to ALL professions!!!! There HAS to be rules governing individuals whom hold this type of power in their hands.
I have to agree with one of the previous comments that not all on the list are actual experiments, but we have certainly produced scientifics results that, in this day and age, could never have happened!!!
152. NsaneNtellect: Psychological adults, those with ethics and morals either learned or built-in, do things the right way, the moral way, whether or not someone is looking.
Only children and damaged adults require guidance or a monitor constantly watching their every move to behave anything approaching ethical behavior.
Our society has a lot to do with this phenomena, but it’s not entirely to blame. This has been true for centuries, for millennia, it’s probably just part of human nature, but is easier to spot and spread now with all of the media at our fingertips.
No matter what, though, the percentage of naturally moral, ethical people will continue to remain the same, perhaps even grow, now that the circumstances require us to be better human beings.
I find it kind of sad that a list like this can be published with so little research, and that so many people take what’s said at face value without critical thought.
How was the milgram study unethical?
Considering #9 a psychology experiment seems quite a stretch.
Much of Peter Gabriel’s music was inspired by the Milgram Experiment, including his fascinating song ”Shock the Monkey.”
Unfortunately, the most unethical studies are some of the most important. 7 out of 10 of these are key studies in Psychology.
Also, David Reimer’s original name was Bruce, he changed it to David after he found out.
Erm – The Milgram experiment was unethical as it allowed the particpant to believe they were giving sever electric shocks to another human being! And if you were one of those in the study who went all the way to the highest setting – and then in the debrief were told it was all a lie – than you would have to live with the fact that you would have knowingly given high voltage FATAL shocks to someone. That could screw you up for life…Definitely unethical.
Wow, the top 10 most unethical experiments eh? Im learning a few of ‘em for my IB course for my diploma atm. And they sure weren’t pleasant.
This is why doctors and psychologists are supposed to follow the code of ethics. SO THAT THINGS LIKE THIS WILL NEVER HAPPEN AGAIN.
#4 doesn’t say why the learned helplessness experiments are unethical-is it because dogs were used? Because they were shocked?
You also don’t report that learned helplessness is a model that has been used time and again to determine the effectiveness of antidepressant drug treatments. It’s not generally used in dogs anymore, but it is used in rodents such as rats and mice and is quite effective as a model of depression.
crack heads
WHAT A PILE OF SH*TE!
Yow dis list iz sik blud. i wud nver let no man burn my cck off.
I like this list.
YOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOW DDDDAWG! DIS IZ FFFFFFFFFFFFFFCCCCCCCCCKKKKKKKKKKKKKEDDDDDDDDDDDDDDDDDDDDDDDD
HAROOON GOT A MASSSSSSSIVE NOSE BLUD!
Yow maya pea head yh?
THIS SH*T IS PENG TING, WHY WOULD DEY TRY DIS SH*T, I SWEAR DOWN, WHO DO THEY THINK DEY ARE, DIS ACUALLY IS LIKE F**CKED UP. DESE BLOODCLUTS NEED TO KEEP THE P**SY HOLES IN DER REACH. ITE DEY R ALL BUMBAS.
DRAW FOR THE SKENG.
XxXxXxXxXxXxX
ARE YOU *****IN DUMB JAM JAM
DONT BAIT OUT GYALS NAME ON DIS TING YOU LITTLE VAGINA
haroons a nob and im a comunist
I Like this list epescially the penis one, i wish i could have mine burned off.
i’d happily burn off haroons penis
sounds like typical NEW WORLD ORDER experiments > try out the present ones that are legal > Chemtrails , H.A.A.R.P ,
artificial sweetners like ASPATRAME E951 ( sweet poison ) in all diet drinks etc chewing gums , read about the latest experiment AGENDA 21 , nearly in place by 2012.
I think these times r a changing
I love it when I find a new list and this one was incredibly interesting. The two that fascinate me the most are the Milgram/Stanford Prison studies. The deep, dark recesses of the human mind. We are a lot more susceptible than we realize.
this is really disturbing to read. i find animal testing an absolute disgrace when it is utterly unneseccary,but to do those kind of things to people(and most of all babies and young children) is appalling.
AWESOME LIST.
Wow, and we wonder why the psychology profession is not always talked about in a good way. These people have helped ruin the good intentions of psychology.
#1 is tragic.
i think #1 is being distorted for the sake of sounding unethical. I’ve learned about this story before, and I’ve never read anything about it being an attempt to prove nurture over nature. It was a mistake made under the assumption of the dominance of nurture, but it wasn’t some sort of deliberate test.
Typo: #9, 2nd para., 2nd line, add an “e” to “discretely”